Our knowledge of cannabis is changing so rapidly that it can be difficult to keep up, no matter how passionate you are about the plant. Humans have been growing and using Cannabis Sativa for centuries, and more recently we have started to seriously study its effects. There is now a growing body of research into the potential medical benefits of cannabis, and in particular the possibilities of the two best knowncannabinoids: THC und CBD.
There are up to100 cannabinoidsin the cannabis plant and it's not easy to keep up with all of them. But if you're wondering what the next "big thing" in the cannabis industry might be, getting familiar with cannabinol (CBN) is probably a good idea.
While CBN has been on the radar of scientists for decades, the researchEnvironment is still limited. But recently there has been a surge of interest in CBN, and it could be one of the next cannabinoids to be developed for its potential medical benefits and effects. In this guide, we bring you up to date with the latest information about CBN, including a comparison to its cousin CBD and its potential uses.
Fast CBN facts
- CBN is a minor cannabinoid compound found in the cannabis plant that has shown the potential to provide multiple health benefits to patients.
- There is still not enough research on CBN to be comprehensive, meaning there is still a long way to go to truly understand this connection.
What is CBN?
CBN is a chemical compound found in low concentrations in cannabis. While it is found in trace amounts in fresh cannabis, it is much more common in older cannabis which has already been dried and stored for some time. The reason for this is that it actually occurs asByproduct of THC deterioration. When THC is exposed to heat, light, and oxygen over time, THC undergoes a process calleddecarboxylation, where it is converted to CBN.
Like the other cannabinoids, CBN's effects are based on its ability to bind to cannabinoid receptors found throughout the human body. There are two main cannabinoid receptors that scientists have identified: CB1 and CB2.
CBN interacts weakly with the CB1 receptor and more strongly with the CB2 receptor. These receptors play a role in regulating a number of processes such as appetite, mood, memory and pain.[Those]
CBN vs. CBD: Similarities and Differences
CBN and CBD share similar names and acronyms, but they definitely areNotthe same. They are both cannabinoids and can be found in the cannabis plant, but they are separate compounds and have their own unique effects. Some of the similarities between CBN and CBD are:
●Both cannabinoids interact with the body's endocannabinoid system.
●Both have similar potential benefits and effects on the body.
●Both have shown very few side effects.
However, there are some important differences between CBD and CBN. Some of these include
●Potential: CBD is one of the most abundant cannabinoids in the plant. There is usually much less CBN, especially in living plants.
●Psychoaktivität:Both CBN and CBD are psychoactive, but while CBN is thought to affect behavior and mood, CBD's effects on the nervous system are milder.
●Bildung:CBN forms in cannabis as THC degrades through age, heat, and light. CBD is formed from CBDa when marijuana is exposed to heat and air.
●Legal Status: CBN is typically grouped with THC and is typically more tightly regulated throughout the US. CBD has a unique legal status and is now considered legal as long as it comes from a cannabis or hemp plant with less than 0.3% THC.[Those]
●Research: CBD is relative well researched so we have a fairly comprehensive understanding of its effects. CBN is still new and we know a lot less about it at this point.
●Cost: CBN products tend to be more expensive than CBD products. This is because CBN is typically more difficult to isolate than CBD and the process takes more time.
What does CBN do? Possible benefits and implications
Now that we understand some of the science behind this cannabinoid, you might be wondering, "What is CBN good for?"
There is currently no definitive answer to this question. The effect of CBN is still relatively unknown. There have been several scientific studies looking at the effects on animals, but not nearly enough to be comprehensive, so more research is needed.
CBN and sleep
Some researchsuggests that CBN enhances the sleep-promoting effects sometimes associated with THC, so it may be useful for relaxation. However, a newer one learnof the CBN literature suggests that "preclinical and clinical research investigating the effects of CBN is outdated and limited" and that there is little evidence to support CBN's sleep-promoting effects. (Basically, there are no clear answers about CBN and sleep, and more research needs to be done.)
CBN is becoming increasingly popular in a variety of products. Apart fromCannabisblüten, find CBN in:
●Evaporation of liquids
To learn more about CBN cannabis products, get personalized recommendations and try them for yourself, visit RISE and connect with our teams of experts.
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Is CBN legal?
Put simply, it depends on where you live.
In the US, recreational marijuana and its extracts are nowlegal in 18 states. Many other states allow the use of medicinal cannabis, although pure CBN and CBN products are not yet widely prescribed by physicians for many conditions.
Note that although many states have legalized recreational and medical marijuana and its extracts, compounds, and derivatives (including CBN) for many purposes, these substances remain illegal at the federal level under the Controlled Substances Act.
Is CBN intoxicating?
CBN can have psychoactive effects, so it is possible for a person to experience intoxication if a person consumes a large amount of it. But the effects are typically very mild compared to THC. In general, most people who consume CBN alone will most likely not experience the same intoxicating effects (such as altered behavior, cognition, etc.) as THC.
Is CBN good for sleep?
There is no definitive answer yet.
So far, there is very little evidence that CBN alone supports sleep. The few studies examining the effects of CBN on humans were insignificant and had limitations in their methodology. So it's still unclear if CBN itself is good for sleep.
However, it is possible that CBN indirectly supports sleep. For example, one of the potential uses of CBN is to treat pain and inflammation. Both pain and inflammation can make it difficult to fall asleep. CBN could help people sleep better by helping alleviate discomfort.
Bottom Line: All of the sleep-promoting effects of the cannabis plant may derive in part from CBN, but they may also derive from CBD, THC, other cannabinoids, terpenes, or the entourage effect as a result of their interaction. Whether or not CBN is partially responsible for the potential sleep-inducing effects of marijuana has yet to be proven.
How long does CBN stay in the body?
The short answer is that we're not sure yet. The longer answer is that it depends on a number of considerations, e.g. B. how much you consume, personal biological factors and others.
One of the main factors affecting how long CBN stays in the body is how you consume it.researchfound that the average half-life of CBN when injected intravenously is 32 hours. The half-life of CBN was 43 hours after smoking cannabis. This means that around half of the CBN will be eliminated 43 hours after smoking cannabis.
- Cannabis (Marijuana) and Cannabinoids: What You Need to Know | National Health Institute
- Sciencedirect.com | Neuroscience Archives | Cannabinol Research
- Sciencedirect.com | Pharmacology and Toxicology Archives | Cannabinol Research
- Zou S, Kumar U. Cannabinoid receptors and the endocannabinoid system: signaling and function in the central nervous system. international J. Mol. Sci. 2018;19(3):833. Published March 13, 2018. doi:10.3390/ijms19030833
- FDA regulation for cannabis and cannabis-derived products, including cannabidiol (CBD)
- Karniol IG, Shirakawa I, Takahashi RN, Knobel E, Musty RE. Effects of Delta9-Tetrahydrocannabinol and Cannabinol in Humans. Pharmacology. 1975;13(6):502-512. doi:10.1159/000136944
- Corroon J. Cannabinol and sleep: separating fact from fiction. Cannabis Cannabinoid Res. 2021;6(5):366-371. doi:10.1089/can.2021.0006
- Zurier, R.B. and Burstein, S.H. (2016), Cannabinoids, inflammation and fibrosis. The FASEB Journal, 30: 3682-3689.https://doi.org/10.1096/fj.201600646R
- Farrimond JA, Whalley BJ, Williams CM. Cannabinol and cannabidiol exert opposing effects on the dietary patterns of rats. Psychopharmacology (Berl). 2012;223(1):117-129. doi:10.1007/s00213-012-2697-x
- Kogan NM, Mechoulam R. Cannabinoids in health and disease. Dialogues Clin Neurosci. 2007;9(4):413-430. doi:10.31887/DCNS.2007.9.4/nkogan
- Giacoppo S, Mazzon E. Can cannabinoids be a potential therapeutic tool in amyotrophic lateral sclerosis?. Neural Regeneration Res. 2016;11(12):1896-1899. doi:10.4103/1673-5374.197125
- Wong H, Cairns BE. Cannabidiol, cannabinol, and their combinations act as peripheral analgesics in a rat model of myofascial pain. Arch Oral Biol. 2019;104:33-39. doi:10.1016/j.archoralbio.2019.05.028
- Sofia RD, Vassar HB, Knobloch LC. Comparative analgesic activity of different naturally occurring cannabinoids in mice and rats. psychopharmacology. 1975;40(4):285-295. doi:10.1007/BF00421466
- Karas JA, Wong LJM, Paulin OKA, et al. The antimicrobial activity of cannabinoids. Antibiotics (Basel). 2020;9(7):406. Published July 13, 2020. doi:10.3390/antibiotics9070406
- Russo EB, Marcu J. Cannabis Pharmacology: The Usual Suspects and Some Promising Leads. Adv. Pharmacol. 2017;80:67-134. doi:10.1016/bs.apha.2017.03.004
- Johansson E, Ohlsson A, Lindgren JE, Agurell S, Gillespie H, Hollister LE. Single-dose kinetics of deuterium-labeled cannabinol in humans after intravenous administration and smoking. Biomed Environ Mass Spectrum. 1987;14(9):495-499. doi:10.1002/bms.1200140904